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Management of Platelet Refractoriness Program Overview

Program Description

The management of the platelet refractory patient presents a challenge for most hospitals and transfusion services. This presentation reviews the pathophysiology and causes of platelet refractoriness. In addition, the presentation reviews current testing methods used for HLA and HPA typing and the detection and identification of alloantibodies that may cause platelet alloimmune refractoriness.

Learning Objectives

Upon completion of the workshop, the participant will be able to:

  • Describe the role of platelets in hemostasis;
  • Describe pathophysiology and causes of platelet refractoriness;
  • Discuss the investigation and diagnosis of refractoriness;
  • Discuss lab tests and management of platelet refractoriness.

Level of Instruction

  • Intermediate

P.A.C.E. Statement

Blood Systems, Inc. is approved as a provider of continuing education programs in the clinical laboratory sciences by the ASCLS P.A.C.E.® Program

In 1977, P.A.C.E.® was established by the American Society of Clinical Laboratory Science (ASCLS) to stimulate and serve as the quality assurance mechanism for continuing education programs offered to clinical laboratory professionals. ASCLS strongly supports continuing education opportunities to increase and enhance professional knowledge and ongoing proficiency. P.A.C.E.® ensures that the continuing education programs offered to clinical laboratory professionals maintain high standards of quality and professional acceptability.

CE Broker Statement

These courses are also approved for Florida continuing education credits for Laboratory Professionals and Nurses through Florida Blood Services Provider # 50-2063. Credits will be reported to CE Broker on a monthly basis. To obtain Florida credits, one must pass the quizzes with a score of 80% or higher. Individuals must choose between P.A.C.E. or Florida credits.

Contact hours

  • Completion of this program will provide 1.0 contact hour of P.A.C.E. continuing education credit.
  • Completion of this program will provide contact hour of Blood Banking Florida CE Broker continuing education credit.

Speaker Credentials

Dolores Figueroa, MT (ASCP) SBB, is an IRL System specialist with Blood Systems, Inc.; she is responsible for the technical direction of the BSI Immunohematology Reference Laboratory reference testing activities. Previously Dolores was the Technical Director for the Blood Systems Laboratories Immunohematology Reference Laboratory (IRL). Dolores joined Blood Systems in July 2000. She holds a certificate in Medical Technology from the University of Puerto Rico, Medical Science Campus. She attended the Atlanta ARC SBB School, and is a certified medical technologist and specialist in blood banking through the American Society of Clinical Pathology (ASCP). The narrator of the presentation is Marie Holub, MA; MT (ASCP) SBB has a Master’s Degree in Education and has worked for Blood Systems for 18 years.

Technical Requirements and Assistance

To view the program material, you need a computer with a supported web browser and a dial-up or better internet connection. The supported operating systems and web browsers are:

Operating Systems

  • Windows 2000, XP, Vista, Windows 7
  • MacOS X 10.4 or later
  • Linux 2.6 with KDE or Gnome

Web Browsers

  • Internet Explorer 6 or later
  • Firefox 2 or later
  • Safari 3 or later
  • Opera 9 or later

Technical Support

Content Questions

Content questions can be directed to, Dolores Figueroa, MT (ASCP) SB at: dfigueroa@bloodsystems.org or (480) 675-5734.

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